Assembly of the Ebola Virus Nucleoprotein from a Chaperoned VP35 Complex

Ebolavirus NP oligomerizes into helical filaments found at the core of the virion, encapsidates the viral RNA genome, and serves as a scaffold for additional viral proteins within the viral nucleocapsid. We identified a portion of the phosphoprotein homolog VP35 that binds with high affinity to nasc...

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Bibliographic Details
Main Authors: Robert N. Kirchdoerfer, Dafna M. Abelson, Sheng Li, Malcolm R. Wood, Erica Ollmann Saphire
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715005860