Structural basis for the dsRNA specificity of the Lassa virus NP exonuclease.

by Kathryn M Hastie, Liam B King, Michelle A Zandonatti, Erica Ollmann Saphire
Published 2012-01-01

The Ebola Virus VP30-NP Interaction Is a Regulator of Viral RNA Synthesis.

by Robert N Kirchdoerfer, Crystal L Moyer, Dafna M Abelson, Erica Ollmann Saphire
Published 2016-10-01

Assembly of the Ebola Virus Nucleoprotein from a Chaperoned VP35 Complex

by Robert N. Kirchdoerfer, Dafna M. Abelson, Sheng Li, Malcolm R. Wood, Erica Ollmann Saphire
Published 2015-07-01

Antibodies to the Glycoprotein GP2 Subunit Cross-React between Old and New World Arenaviruses

by Fatima Amanat, James Duehr, Lisa Oestereich, Kathryn M. Hastie, Erica Ollmann Saphire, Florian Krammer
Published 2018-05-01

Ebola virus glycoprotein needs an additional trigger, beyond proteolytic priming for membrane fusion.

by Shridhar Bale, Tong Liu, Sheng Li, Yuhao Wang, Dafna Abelson, Marnie Fusco, Virgil L Woods, Erica Ollmann Saphire
Published 2011-11-01

Sudan Ebolavirus VP35-NP Crystal Structure Reveals a Potential Target for Pan-Filovirus Treatment

by Sara Landeras-Bueno, Shun-ichiro Oda, Michael J. Norris, Zhe Li Salie, Javier Guenaga, Richard T. Wyatt, Erica Ollmann Saphire
Published 2019-07-01

Diverse Morphology and Structural Features of Old and New World Hantaviruses

by Amar Parvate, Evan P. Williams, Mariah K. Taylor, Yong-Kyu Chu, Jason Lanman, Erica Ollmann Saphire, Colleen B. Jonsson
Published 2019-09-01

Structural Basis of Pan-Ebolavirus Neutralization by a Human Antibody against a Conserved, yet Cryptic Epitope

by Brandyn R. West, Crystal L. Moyer, Liam B. King, Marnie L. Fusco, Jacob C. Milligan, Sean Hui, Erica Ollmann Saphire
Published 2018-09-01

Antibody Repertoires to the Same Ebola Vaccine Antigen Are Differentially Affected by Vaccine Vectors

by Michelle Meyer, Asuka Yoshida, Palaniappan Ramanathan, Erica Ollmann Saphire, Peter L. Collins, James E. Crowe, Jr., Siba Samal, Alexander Bukreyev
Published 2018-08-01

Host-Primed Ebola Virus GP Exposes a Hydrophobic NPC1 Receptor-Binding Pocket, Revealing a Target for Broadly Neutralizing Antibodies

by Zachary A. Bornholdt, Esther Ndungo, Marnie L. Fusco, Shridhar Bale, Andrew I. Flyak, James E. Crowe, Kartik Chandran, Erica Ollmann Saphire
Published 2016-02-01

Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers

by William Wan, Mairi Clarke, Michael J Norris, Larissa Kolesnikova, Alexander Koehler, Zachary A Bornholdt, Stephan Becker, Erica Ollmann Saphire, John AG Briggs
Published 2020-10-01

The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel, pyramidal fold.

by Adrianna P P Zhang, Zachary A Bornholdt, Tong Liu, Dafna M Abelson, David E Lee, Sheng Li, Virgil L Woods, Erica Ollmann Saphire
Published 2012-02-01

Correction: The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold.

by Adrianna P. P. Zhang, Zachary A. Bornholdt, Tong Liu, Dafna M. Abelson, David E. Lee, Sheng Li, Virgil L. Woods, Erica Ollmann Saphire
Published 2013-12-01

Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form

by Sara Landeras-Bueno, Hal Wasserman, Glenn Oliveira, Zachary L. VanAernum, Florian Busch, Zhe Li Salie, Vicki H. Wysocki, Kristian Andersen, Erica Ollmann Saphire
Published 2021-04-01

Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk

by Liam B. King, Brandyn R. West, Crystal L. Moyer, Pavlo Gilchuk, Andrew Flyak, Philipp A. Ilinykh, Robin Bombardi, Sean Hui, Kai Huang, Alexander Bukreyev, James E. Crowe, Erica Ollmann Saphire
Published 2019-04-01

Structural Basis for Differential Neutralization of Ebolaviruses

by John M. Dye, Erica Ollmann Saphire, Kartik Chandran, Virgil L. Woods, Sheng Li, Tong Liu, Ana I. Keuhne, Anthony C. Wong, Marnie L. Fusco, Takao Hashiguchi, Shridhar Bale, Joao M. Dias
Published 2012-04-01

Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry.

by Adam Schafer, Rui Xiong, Laura Cooper, Raghad Nowar, Hyun Lee, Yangfeng Li, Benjamin E Ramirez, Norton P Peet, Michael Caffrey, Gregory R J Thatcher, Erica Ollmann Saphire, Han Cheng, Lijun Rong
Published 2021-02-01

Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism.

by Shridhar Bale, Jean-Philippe Julien, Zachary A Bornholdt, Christopher R Kimberlin, Peter Halfmann, Michelle A Zandonatti, John Kunert, Gerard J A Kroon, Yoshihiro Kawaoka, Ian J MacRae, Ian A Wilson, Erica Ollmann Saphire
Published 2012-09-01

Reporter Assays for Ebola Virus Nucleoprotein Oligomerization, Virion-Like Particle Budding, and Minigenome Activity Reveal the Importance of Nucleoprotein Amino Acid Position 111

by Aaron E. Lin, William E. Diehl, Yingyun Cai, Courtney L. Finch, Chidiebere Akusobi, Robert N. Kirchdoerfer, Laura Bollinger, Stephen F. Schaffner, Elizabeth A. Brown, Erica Ollmann Saphire, Kristian G. Andersen, Jens H. Kuhn, Jeremy Luban, Pardis C. Sabeti
Published 2020-01-01

An intranasal vaccine durably protects against SARS-CoV-2 variants in mice

by Ahmed O. Hassan, Swathi Shrihari, Matthew J. Gorman, Baoling Ying, Dansu Yaun, Saravanan Raju, Rita E. Chen, Igor P. Dmitriev, Elena Kashentseva, Lucas J. Adams, Colin Mann, Meredith E. Davis-Gardner, Mehul S. Suthar, Pei-Yong Shi, Erica Ollmann Saphire, Daved H. Fremont, David T. Curiel, Galit Alter, Michael S. Diamond
Published 2021-07-01