Peptide-Like Nylon-3 Polymers with Activity against Phylogenetically Diverse, Intrinsically Drug-Resistant Pathogenic Fungi

Fungi reside in all ecosystems on earth and impart both positive and negative effects on human, plant, and animal health. Fungal disease is on the rise worldwide, and there is a critical need for more effective and less toxic antifungal agents. Nylon-3 polymers are short, sequence random, poly-β-ami...

Full description

Bibliographic Details
Main Authors: Leslie A. Rank, Naomi M. Walsh, Fang Yun Lim, Samuel H. Gellman, Nancy P. Keller, Christina M. Hull
Format: Article
Language:English
Published: American Society for Microbiology 2018-05-01
Series:mSphere
Subjects:
Online Access:https://doi.org/10.1128/mSphere.00223-18