An LaeA- and BrlA-Dependent Cellular Network Governs Tissue-Specific Secondary Metabolism in the Human Pathogen Aspergillus fumigatus

by Abigail L. Lind, Fang Yun Lim, Alexandra A. Soukup, Nancy P. Keller, Antonis Rokas, Aaron P. Mitchell
Published 2018-03-01

Peptide-Like Nylon-3 Polymers with Activity against Phylogenetically Diverse, Intrinsically Drug-Resistant Pathogenic Fungi

by Leslie A. Rank, Naomi M. Walsh, Fang Yun Lim, Samuel H. Gellman, Nancy P. Keller, Christina M. Hull
Published 2018-05-01

Fungal Isocyanide Synthases and Xanthocillin Biosynthesis in Aspergillus fumigatus

by Fang Yun Lim, Tae Hyung Won, Nicholas Raffa, Joshua A. Baccile, Jen Wisecaver, Antonis Rokas, Frank C. Schroeder, Nancy P. Keller
Published 2018-05-01

Contributions of Spore Secondary Metabolites to UV-C Protection and Virulence Vary in Different Aspergillus fumigatus Strains

by Adriana Blachowicz, Nicholas Raffa, Jin Woo Bok, Tsokyi Choera, Benjamin Knox, Fang Yun Lim, Anna Huttenlocher, Clay C. C. Wang, Kasthuri Venkateswaran, Nancy P. Keller
Published 2020-02-01

Low-volume toolbox for the discovery of immunosuppressive fungal secondary metabolites.

by Erwin Berthier, Fang Yun Lim, Qing Deng, Chun-Jun Guo, Dimitrios P Kontoyiannis, Clay C C Wang, Julie Rindy, David J Beebe, Anna Huttenlocher, Nancy P Keller
Published 2013-01-01

FleA Expression in Aspergillus fumigatus Is Recognized by Fucosylated Structures on Mucins and Macrophages to Prevent Lung Infection.

by Sheena C Kerr, Gregory J Fischer, Meenal Sinha, Orla McCabe, Jonathan M Palmer, Tsokyi Choera, Fang Yun Lim, Michaela Wimmerova, Stephen D Carrington, Shaopeng Yuan, Clifford A Lowell, Stefan Oscarson, Nancy P Keller, John V Fahy
Published 2016-04-01

Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense

by Philipp Wiemann, Adi Perevitsky, Fang Yun Lim, Yana Shadkchan, Benjamin P. Knox, Julio A. Landero Figueora, Tsokyi Choera, Mengyao Niu, Andrew J. Steinberger, Marcel Wüthrich, Rachel A. Idol, Bruce S. Klein, Mary C. Dinauer, Anna Huttenlocher, Nir Osherov, Nancy P. Keller
Published 2017-05-01

Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense

by Philipp Wiemann, Adi Perevitsky, Fang Yun Lim, Yana Shadkchan, Benjamin P. Knox, Julio A. Landero Figueora, Tsokyi Choera, Mengyao Niu, Andrew J. Steinberger, Marcel Wüthrich, Rachel A. Idol, Bruce S. Klein, Mary C. Dinauer, Anna Huttenlocher, Nir Osherov, Nancy P. Keller
Published 2017-06-01

Revitalization of a Forward Genetic Screen Identifies Three New Regulators of Fungal Secondary Metabolism in the Genus Aspergillus

by Brandon T. Pfannenstiel, Xixi Zhao, Jennifer Wortman, Philipp Wiemann, Kurt Throckmorton, Joseph E. Spraker, Alexandra A. Soukup, Xingyu Luo, Daniel L. Lindner, Fang Yun Lim, Benjamin P. Knox, Brian Haas, Gregory J. Fischer, Tsokyi Choera, Robert A. E. Butchko, Jin-Woo Bok, Katharyn J. Affeldt, Nancy P. Keller, Jonathan M. Palmer, B. Gillian Turgeon
Published 2017-09-01