Adenomatous Polyposis Coli-Mediated Accumulation of Abasic DNA Lesions Lead to Cigarette Smoke Condensate-Induced Neoplastic Transformation of Normal Breast Epithelial Cells

Adenomatous Polyposis Coli-Mediated Accumulation of Abasic DNA Lesions Lead to Cigarette Smoke Condensate-Induced Neoplastic Transformation of Normal Breast Epithelial Cells

Adenomatous polyposis coli (APC) is a multifunctional protein having diverse cellular functions including cell migration, cell-cell adhesion, cell cycle control, chromosomal segregation, and apoptosis. Recently, we found a new role of APC in base excision repair (BER) and showed that it interacts w...

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Bibliographic Details
Main Authors: Aruna S. Jaiswal, Harekrushna Panda, Christine A. Pampo, Dietmar W. Siemann, C. Gary Gairola, Robert Hromas, Satya Narayan
Format: Article
Language:English
Published: Elsevier 2013-04-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613800528

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http://www.sciencedirect.com/science/article/pii/S1476558613800528

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