The Role of PCNA Posttranslational Modifications in Translesion Synthesis

by Montaser Shaheen, Ilanchezhian Shanmugam, Robert Hromas
Published 2010-01-01

The SET Domain Is Essential for Metnase Functions in Replication Restart and the 5' End of SS-Overhang Cleavage.

by Hyun-Suk Kim, Sung-Kyung Kim, Robert Hromas, Suk-Hee Lee
Published 2015-01-01

The Safe Path at the Fork: Ensuring Replication-Associated DNA Double-Strand Breaks are Repaired by Homologous Recombination

by Jac A. Nickoloff, Neelam Sharma, Lynn Taylor, Sage J. Allen, Robert Hromas
Published 2021-09-01

NSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer Cel...

by Aruna S Jaiswal, Harekrushna Panda, Brian K Law, Jay Sharma, Jitesh Jani, Robert Hromas, Satya Narayan
Published 2015-01-01

Adenomatous Polyposis Coli-Mediated Accumulation of Abasic DNA Lesions Lead to Cigarette Smoke Condensate-Induced Neoplastic Transformation of Normal Breast Epithelial Cells

by Aruna S. Jaiswal, Harekrushna Panda, Christine A. Pampo, Dietmar W. Siemann, C. Gary Gairola, Robert Hromas, Satya Narayan
Published 2013-04-01

Metnase mediates resistance to topoisomerase II inhibitors in breast cancer cells.

by Justin Wray, Elizabeth A Williamson, Melanie Royce, Montaser Shaheen, Brian D Beck, Suk-Hee Lee, Jac A Nickoloff, Robert Hromas
Published 2009-01-01

Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection.

by Katherine Sullivan, Kimberly Cramer-Morales, Daniel L McElroy, David A Ostrov, Kimberly Haas, Wayne Childers, Robert Hromas, Tomasz Skorski
Published 2016-01-01

DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response

by Fengshan Liang, Adam S. Miller, Simonne Longerich, Caroline Tang, David Maranon, Elizabeth A. Williamson, Robert Hromas, Claudia Wiese, Gary M. Kupfer, Patrick Sung
Published 2019-06-01

Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies

by Yonghan He, Sajid Khan, Zhiguang Huo, Dongwen Lv, Xuan Zhang, Xingui Liu, Yaxia Yuan, Robert Hromas, Mingjiang Xu, Guangrong Zheng, Daohong Zhou
Published 2020-07-01

The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells

by Robert Hromas, Hyun-Suk Kim, Gurjit Sidhu, Elizabeth Williamson, Aruna Jaiswal, Taylor A. Totterdale, Jocelyn Nole, Suk-Hee Lee, Jac A. Nickoloff, Kimi Y. Kong
Published 2017-11-01

A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel disease.

by Maegan L Capitano, Aruna Jaiswal, Hal E Broxmeyer, Yilianys Pride, Sarah Glover, Fatemah G Amlashi, Austin Kirby, Gayathri Srinivasan, Elizabeth A Williamson, Daniel Mais, Robert Hromas
Published 2021-01-01

Sweet-Tasting Ionic Conjugates of Local Anesthetics and Vasoconstrictors

by John K. Neubert, Alexander A. Oliferenko, Polina V. Oliferenko, Sergey V. Emets, David A. Ostrov, Gary I. Altschuler, Joe Calkins, Jay Wickersham, Robert Hromas, Iryna O. Lebedyeva
Published 2021-02-01

Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions

by James M. Daley, Nozomi Tomimatsu, Grace Hooks, Weibin Wang, Adam S. Miller, Xiaoyu Xue, Kevin A. Nguyen, Hardeep Kaur, Elizabeth Williamson, Bipasha Mukherjee, Robert Hromas, Sandeep Burma, Patrick Sung
Published 2020-06-01

Neoamphimedine Circumvents Metnase-Enhanced DNA Topoisomerase IIα Activity Through ATP-Competitive Inhibition

by Philip Reigan, Brian G. Reid, Qiong Zhou, Amanda K. Ashley, Jac A. Nickoloff, Robert Hromas, Daniel V. LaBarbera, Courtney L. Amerin, Qun Li, Adedoyin D. Abraham, Byong Hoon Yoo, Jessica Ponder
Published 2011-11-01