Functional amyloid formation within mammalian tissue.

Amyloid is a generally insoluble, fibrous cross-beta sheet protein aggregate. The process of amyloidogenesis is associated with a variety of neurodegenerative diseases including Alzheimer, Parkinson, and Huntington disease. We report the discovery of an unprecedented functional mammalian amyloid str...

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Bibliographic Details
Main Authors: Douglas M Fowler, Atanas V Koulov, Christelle Alory-Jost, Michael S Marks, William E Balch, Jeffery W Kelly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0040006