Group I p21-activated kinases in leukemia cell adhesion to fibronectin
P21-activated kinases (PAK) regulate processes associated with cytoskeleton dynamics. PAK expression in leukemia cells was measured on protein and mRNA levels. In functional assays, we analyzed the effect of PAK inhibitors IPA-3 and FRAX597 on cell adhesivity and viability. PAK2 was dominant in cell...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2021-01-01
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Series: | Cell Adhesion & Migration |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/19336918.2021.1872760 |