Generation of Reactive Oxygen Species during Apoptosis Induced by DNA-Damaging Agents and/or Histone Deacetylase Inhibitors

by Barbora Brodská, Aleš Holoubek
Published 2011-01-01

Decitabine and SAHA-Induced Apoptosis Is Accompanied by Survivin Downregulation and Potentiated by ATRA in p53-Deficient Cells

by Barbora Brodská, Petra Otevřelová, Aleš Holoubek
Published 2014-01-01

Localization of AML-related nucleophosmin mutant depends on its subtype and is highly affected by its interaction with wild-type NPM.

by Barbora Brodská, Markéta Kráčmarová, Aleš Holoubek, Kateřina Kuželová
Published 2017-01-01

Combined Treatment with Low Concentrations of Decitabine and SAHA Causes Cell Death in Leukemic Cell Lines but Not in Normal Peripheral Blood Lymphocytes

by Barbora Brodská, Aleš Holoubek, Petra Otevřelová, Kateřina Kuželová
Published 2013-01-01

Group I PAK inhibitor IPA-3 induces cell death and affects cell adhesivity to fibronectin in human hematopoietic cells.

by Kateřina Kuželová, Dana Grebeňová, Aleš Holoubek, Pavla Röselová, Adam Obr
Published 2014-01-01

AML-Related NPM Mutations Drive p53 Delocalization into the Cytoplasm with Possible Impact on p53-Dependent Stress Response

by Aleš Holoubek, Dita Strachotová, Petra Otevřelová, Pavla Röselová, Petr Heřman, Barbora Brodská
Published 2021-06-01

Group I p21-activated kinases in leukemia cell adhesion to fibronectin

by Kateřina Kuželová, Adam Obr, Pavla Röselová, Dana Grebeňová, Petra Otevřelová, Barbora Brodská, Aleš Holoubek
Published 2021-01-01

NSC348884 cytotoxicity is not mediated by inhibition of nucleophosmin oligomerization

by Markéta Šašinková, Petr Heřman, Aleš Holoubek, Dita Strachotová, Petra Otevřelová, Dana Grebeňová, Kateřina Kuželová, Barbora Brodská
Published 2021-01-01