Finding missing heritability in less significant Loci and allelic heterogeneity: genetic variation in human height.

Finding missing heritability in less significant Loci and allelic heterogeneity: genetic variation in human height.

Genome-wide association studies (GWAS) have identified many common variants associated with complex traits in human populations. Thus far, most reported variants have relatively small effects and explain only a small proportion of phenotypic variance, leading to the issues of 'missing' her...

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Bibliographic Details
Main Authors: Ge Zhang, Rebekah Karns, Guangyun Sun, Subba Rao Indugula, Hong Cheng, Dubravka Havas-Augustin, Natalija Novokmet, Zijad Durakovic, Sasa Missoni, Ranajit Chakraborty, Pavao Rudan, Ranjan Deka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3521016?pdf=render

Internet

http://europepmc.org/articles/PMC3521016?pdf=render

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