Liver Proliferation Is an Essential Driver of Fibrosis in Mouse Models of Nonalcoholic Fatty Liver Disease

by Ashley Cast, Meenasri Kumbaji, Amber D'Souza, Katherine Rodriguez, Anita Gupta, Rebekah Karns, Lubov Timchenko, Nikolai Timchenko
Published 2019-08-01

CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro.

by Jason T Blackard, Ling Kong, Susan D Rouster, Rebekah Karns, Paul S Horn, Shyam Kottilil, M Tarek Shata, Kenneth E Sherman
Published 2019-01-01

Elimination of Age-Associated Hepatic Steatosis and Correction of Aging Phenotype by Inhibition of cdk4-C/EBPα-p300 Axis

by Phuong Nguyen, Leila Valanejad, Ashley Cast, Mary Wright, Jose M. Garcia, Hashem B. El-Serag, Rebekah Karns, Nikolai A. Timchenko
Published 2018-08-01

Common SNPs in FTO gene are associated with obesity related anthropometric traits in an island population from the eastern Adriatic coast of Croatia.

by Ge Zhang, Rebekah Karns, Nina Smolej Narancic, Guangyun Sun, Hong Cheng, Sasa Missoni, Zijad Durakovic, Pavao Rudan, Ranajit Chakraborty, Ranjan Deka
Published 2010-04-01

Gankyrin Promotes Tumor-Suppressor Protein Degradation to Drive Hepatocyte ProliferationSummary

by Amber M. D’Souza, Yanjun Jiang, Ashley Cast, Leila Valanejad, Mary Wright, Kyle Lewis, Meenasri Kumbaji, Sheeniza Shah, David Smithrud, Rebekah Karns, Soona Shin, Nikolai Timchenko
Published 2018-01-01

Finding missing heritability in less significant Loci and allelic heterogeneity: genetic variation in human height.

by Ge Zhang, Rebekah Karns, Guangyun Sun, Subba Rao Indugula, Hong Cheng, Dubravka Havas-Augustin, Natalija Novokmet, Zijad Durakovic, Sasa Missoni, Ranajit Chakraborty, Pavao Rudan, Ranjan Deka
Published 2012-01-01

Extent of height variability explained by known height-associated genetic variants in an isolated population of the Adriatic coast of Croatia.

by Ge Zhang, Rebekah Karns, Guangyun Sun, Subba Rao Indugula, Hong Cheng, Dubravka Havas-Augustin, Natalija Novokmet, Dusko Rudan, Zijad Durakovic, Sasa Missoni, Ranajit Chakraborty, Pavao Rudan, Ranjan Deka
Published 2011-01-01

Modulation of ambient temperature promotes inflammation and initiates atherosclerosis in wild type C57BL/6 mice

by Daniel A. Giles, Bhama Ramkhelawon, Elizabeth M. Donelan, Traci E. Stankiewicz, Susan B. Hutchison, Rajib Mukherjee, Monica Cappelletti, Rebekah Karns, Christopher L. Karp, Kathryn J. Moore, Senad Divanovic
Published 2016-11-01

Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells

by Kodandaramireddy Nalapareddy, Kalpana J. Nattamai, Rupali S. Kumar, Rebekah Karns, Kathryn A. Wikenheiser-Brokamp, Leesa L. Sampson, Maxime M. Mahe, Nambirajan Sundaram, Mary-Beth Yacyshyn, Bruce Yacyshyn, Michael A. Helmrath, Yi Zheng, Hartmut Geiger
Published 2017-03-01

Serum Matrix Metalloproteinase 7 Is a Diagnostic Biomarker of Biliary Injury and Fibrosis in Pediatric Autoimmune Liver Disease

by Simon Lam, Ruchi Singh, Jonathan R. Dillman, Andrew T. Trout, Suraj D. Serai, Divya Sharma, Rachel Sheridan, Weizhe Su, Lin Fei, Rebekah Karns, Marija M. Haramija, Ged Ridgway, Marc Goldfinger, James E. Squires, Lee A. Denson, Jeffery S. Hyams, Alexander G. Miethke
Published 2020-11-01

Type I interferon sensing unlocks dormant adipocyte inflammatory potential

by Calvin C. Chan, Michelle S. M. A. Damen, Maria E. Moreno-Fernandez, Traci E. Stankiewicz, Monica Cappelletti, Pablo C. Alarcon, Jarren R. Oates, Jessica R. Doll, Rajib Mukherjee, Xiaoting Chen, Rebekah Karns, Matthew T. Weirauch, Michael A. Helmrath, Thomas H. Inge, Senad Divanovic
Published 2020-06-01

A BAFF/APRIL axis regulates obesogenic diet-driven weight gain

by Calvin C. Chan, Isaac T. W. Harley, Paul T. Pfluger, Aurelien Trompette, Traci E. Stankiewicz, Jessica L. Allen, Maria E. Moreno-Fernandez, Michelle S. M. A. Damen, Jarren R. Oates, Pablo C. Alarcon, Jessica R. Doll, Matthew J. Flick, Leah M. Flick, Joan Sanchez-Gurmaches, Rajib Mukherjee, Rebekah Karns, Michael Helmrath, Thomas H. Inge, Stuart P. Weisberg, Sünje J. Pamp, David A. Relman, Randy J. Seeley, Matthias H. Tschöp, Christopher L. Karp, Senad Divanovic
Published 2021-05-01

Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

by Yael Haberman, Rebekah Karns, Phillip J. Dexheimer, Melanie Schirmer, Judith Somekh, Ingrid Jurickova, Tzipi Braun, Elizabeth Novak, Laura Bauman, Margaret H. Collins, Angela Mo, Michael J. Rosen, Erin Bonkowski, Nathan Gotman, Alison Marquis, Mason Nistel, Paul A. Rufo, Susan S. Baker, Cary G. Sauer, James Markowitz, Marian D. Pfefferkorn, Joel R. Rosh, Brendan M. Boyle, David R. Mack, Robert N. Baldassano, Sapana Shah, Neal S. Leleiko, Melvin B. Heyman, Anne M. Grifiths, Ashish S. Patel, Joshua D. Noe, Bruce J. Aronow, Subra Kugathasan, Thomas D. Walters, Greg Gibson, Sonia Davis Thomas, Kevin Mollen, Shai Shen-Orr, Curtis Huttenhower, Ramnik J. Xavier, Jeffrey S. Hyams, Lee A. Denson
Published 2019-01-01