Genomic aberrations in an African American colorectal cancer cohort reveals a MSI-specific profile and chromosome X amplification in male patients.

Genomic aberrations in an African American colorectal cancer cohort reveals a MSI-specific profile and chromosome X amplification in male patients.

DNA aberrations that cause colorectal cancer (CRC) occur in multiple steps that involve microsatellite instability (MSI) and chromosomal instability (CIN). Herein, we studied CRCs from AA patients for their CIN and MSI status.Array CGH was performed on 30 AA colon tumors. The MSI status was establis...

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Bibliographic Details
Main Authors: Hassan Brim, Edward Lee, Mones S Abu-Asab, Mohamed Chaouchi, Hadi Razjouyan, Hassanzadeh Namin, Ajay Goel, Alejandro A Schäffer, Hassan Ashktorab
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3412863?pdf=render

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http://europepmc.org/articles/PMC3412863?pdf=render

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