CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro.
<h4>Background and aim</h4>The hepatitis C virus (HCV) is a single-strand RNA virus that infects millions of people worldwide. Recent advances in therapy have led to viral cure using two- and three- drug combinations of direct acting inhibitors of viral replication. CCR5 is a chemokine r...
Main Authors: | Jason T Blackard, Ling Kong, Susan D Rouster, Rebekah Karns, Paul S Horn, Shyam Kottilil, M Tarek Shata, Kenneth E Sherman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0224523 |
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