CCR5 receptor antagonism inhibits hepatitis C virus (HCV) replication in vitro.

<h4>Background and aim</h4>The hepatitis C virus (HCV) is a single-strand RNA virus that infects millions of people worldwide. Recent advances in therapy have led to viral cure using two- and three- drug combinations of direct acting inhibitors of viral replication. CCR5 is a chemokine r...

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Bibliographic Details
Main Authors: Jason T Blackard, Ling Kong, Susan D Rouster, Rebekah Karns, Paul S Horn, Shyam Kottilil, M Tarek Shata, Kenneth E Sherman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224523