Insulin sensitivity regulates cholesterol metabolism to a greater extent than obesity: lessons from the METSIM Study1

Insulin sensitivity regulates cholesterol metabolism to a greater extent than obesity: lessons from the METSIM Study1

Cholesterol synthesis is upregulated and absorption downregulated in insulin resistance and in type 2 dia-betes. We investigated whether alterations in cholesterol metabolism are observed across the glucose tolerance status, from normoglycemia through impaired glucose tolerance to type 2 diabetes, i...

Full description

Bibliographic Details
Main Authors: Helena Gylling, Maarit Hallikainen, Jussi Pihlajamäki, Piia Simonen, Johanna Kuusisto, Markku Laakso, Tatu A. Miettinen
Format: Article
Language:English
Published: Elsevier 2010-08-01
Series:Journal of Lipid Research
Subjects:
Metabolic Syndrome in Men
lathosterol
sitosterol
cholestanol
type 2 diabetes
insulin resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520370784

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520370784

Similar Items