M2 polarization enhances silica nanoparticle uptake by macrophages

M2 polarization enhances silica nanoparticle uptake by macrophages

While silica nanoparticles have enabled numerous industrial and medical applications, their toxicological safety requires further evaluation. Macrophages are the major cell population responsible for nanoparticle clearance in vivo. The prevailing macrophage phenotype largely depends on the local imm...

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Bibliographic Details
Main Authors: Jessica eHoppstädter, Michelle eSeif, Anna eDembek, Christian eCavelius, Hanno eHuwer, Annette eKraegeloh, Alexandra K Kiemer
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Pharmacology
Subjects:
Endocytosis
Inflammation
Phagocytosis
Real-Time PCR
alveolar macrophage
Phagocyte
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00055/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2015.00055/full

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