The enteropathogenic E. coli (EPEC) Tir effector inhibits NF-κB activity by targeting TNFα receptor-associated factors.
Enteropathogenic Escherichia coli (EPEC) disease depends on the transfer of effector proteins into epithelia lining the human small intestine. EPEC E2348/69 has at least 20 effector genes of which six are located with the effector-delivery system genes on the Locus of Enterocyte Effacement (LEE) Pat...
Main Authors: | Marie-Hélène Ruchaud-Sparagano, Sabrina Mühlen, Paul Dean, Brendan Kenny |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-12-01
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Series: | PLoS Pathogens |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22144899/pdf/?tool=EBI |
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