The enteropathogenic E. coli (EPEC) Tir effector inhibits NF-κB activity by targeting TNFα receptor-associated factors.

Enteropathogenic Escherichia coli (EPEC) disease depends on the transfer of effector proteins into epithelia lining the human small intestine. EPEC E2348/69 has at least 20 effector genes of which six are located with the effector-delivery system genes on the Locus of Enterocyte Effacement (LEE) Pat...

Full description

Bibliographic Details
Main Authors: Marie-Hélène Ruchaud-Sparagano, Sabrina Mühlen, Paul Dean, Brendan Kenny
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22144899/pdf/?tool=EBI