Basement membrane-rich organoids with functional human blood vessels are permissive niches for human breast cancer metastasis.

Metastatic breast cancer is the leading cause of death by malignancy in women worldwide. Tumor metastasis is a multistep process encompassing local invasion of cancer cells at primary tumor site, intravasation into the blood vessel, survival in systemic circulation, and extravasation across the endo...

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Bibliographic Details
Main Authors: Rodrigo Fernández-Periáñez, Irene Molina-Privado, Federico Rojo, Irene Guijarro-Muñoz, Vanesa Alonso-Camino, Sandra Zazo, Marta Compte, Ana Alvarez-Cienfuegos, Angel M Cuesta, David Sánchez-Martín, Ana M Alvarez-Méndez, Laura Sanz, Luis Alvarez-Vallina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23951338/?tool=EBI