An alternative pathway for membrane protein biogenesis at the endoplasmic reticulum
O’Keefe et al. investigate the integration of type III single-pass transmembrane proteins targeted to the ER and examine the roles of the ER membrane complex, Sec61 complex and signal recognition particle receptor. As a result, the authors propose an alternative mechanism of insertion, reconciling t...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2021-07-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02363-z |