A Recombination Directionality Factor Controls the Cell Type-Specific Activation of σK and the Fidelity of Spore Development in Clostridium difficile.

A Recombination Directionality Factor Controls the Cell Type-Specific Activation of σK and the Fidelity of Spore Development in Clostridium difficile.

The strict anaerobe Clostridium difficile is the most common cause of nosocomial diarrhea, and the oxygen-resistant spores that it forms have a central role in the infectious cycle. The late stages of sporulation require the mother cell regulatory protein σK. In Bacillus subtilis, the onset of σK ac...

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Bibliographic Details
Main Authors: Mónica Serrano, Nicolas Kint, Fátima C Pereira, Laure Saujet, Pierre Boudry, Bruno Dupuy, Adriano O Henriques, Isabelle Martin-Verstraete
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5025042?pdf=render

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http://europepmc.org/articles/PMC5025042?pdf=render

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