Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools

Background: Diabetes and metabolic syndromes are chronic, devastating diseases with increasing prevalence. Human pluripotent stem cells are gaining popularity in their usage for human in vitro disease modeling. With recent rapid advances in genome editing tools, these cells can now be genetically ma...

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Bibliographic Details
Main Authors: Adrian Kee Keong Teo, Manoj K. Gupta, Alessandro Doria, Rohit N. Kulkarni
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877815001192