Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells

Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells

Vascular endothelial cell (EC) function depends on appropriate organ-specific molecular and cellular specializations. To explore genomic mechanisms that control this specialization, we have analyzed and compared the transcriptome, accessible chromatin, and DNA methylome landscapes from mouse brain,...

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Bibliographic Details
Main Authors: Mark F Sabbagh, Jacob S Heng, Chongyuan Luo, Rosa G Castanon, Joseph R Nery, Amir Rattner, Loyal A Goff, Joseph R Ecker, Jeremy Nathans
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-09-01
Series:eLife
Subjects:
vascular endothelial cell
DNA methylation
accessible chromatin
blood-brain barrier
Wnt
single cell RNA-seq
Online Access:https://elifesciences.org/articles/36187

Internet

https://elifesciences.org/articles/36187

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