Environmental enrichment normalizes hippocampal timing coding in a malformed hippocampus.

Neurodevelopmental insults leading to malformations of cortical development (MCD) are a common cause of psychiatric disorders, learning impairments and epilepsy. In the methylazoxymethanol (MAM) model of MCDs, animals have impairments in spatial cognition that, remarkably, are improved by post-weani...

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Bibliographic Details
Main Authors: Amanda E Hernan, J Matthew Mahoney, Willie Curry, Greg Richard, Marcella M Lucas, Andrew Massey, Gregory L Holmes, Rod C Scott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5796690?pdf=render