Chromatin modification by PSC occurs at one PSC per nucleosome and does not require the acidic patch of histone H2A.

Chromatin architecture is regulated through both enzymatic and non-enzymatic activities. For example, the Polycomb Group (PcG) proteins maintain developmental gene silencing using an array of chromatin-based mechanisms. The essential Drosophila PcG protein, Posterior Sex Combs (PSC), compacts chroma...

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Bibliographic Details
Main Authors: Stanley M Lo, Kyle A McElroy, Nicole J Francis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3469540?pdf=render