Regional mucosa-associated microbiota determine physiological expression of TLR2 and TLR4 in murine colon.

Many colonic mucosal genes that are highly regulated by microbial signals are differentially expressed along the rostral-caudal axis. This would suggest that differences in regional microbiota exist, particularly mucosa-associated microbes that are less likely to be transient. We therefore explored...

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Bibliographic Details
Main Authors: Yunwei Wang, Suzanne Devkota, Mark W Musch, Bana Jabri, Cathryn Nagler, Dionysios A Antonopoulos, Alexander Chervonsky, Eugene B Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2962643?pdf=render