Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq

Identifying gene expression programs of cell-type identity and cellular activity with single-cell RNA-Seq

Identifying gene expression programs underlying both cell-type identity and cellular activities (e.g. life-cycle processes, responses to environmental cues) is crucial for understanding the organization of cells and tissues. Although single-cell RNA-Seq (scRNA-Seq) can quantify transcripts in indivi...

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Bibliographic Details
Main Authors: Dylan Kotliar, Adrian Veres, M Aurel Nagy, Shervin Tabrizi, Eran Hodis, Douglas A Melton, Pardis C Sabeti
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-07-01
Series:eLife
Subjects:
gene expression programs
single-cell Rna-Seq
matrix factorization
visual cortex
brain organoids
synaptogenesis
Online Access:https://elifesciences.org/articles/43803

Internet

https://elifesciences.org/articles/43803

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