An uncommon t(9;11)(p24;q22) with monoallelic loss of ATM and KMT2A genes in a child with myelodysplastic syndrome/acute myeloid leukemia who evolved from Fanconi anemia

An uncommon t(9;11)(p24;q22) with monoallelic loss of ATM and KMT2A genes in a child with myelodysplastic syndrome/acute myeloid leukemia who evolved from Fanconi anemia

Abstract Background Myelodysplastic syndrome (MDS) is rare in the pediatric age group and it may be associated with inheritable bone marrow failure (BMF) such as Fanconi anemia (FA). FA is a rare multi-system genetic disorder, characterized by congenital malformations and progressive BMF. Patients w...

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Bibliographic Details
Main Authors: Viviane Lamim Lovatel, Daiane Corrêa de Souza, Tatiana Fonseca Alvarenga, Roberto R. Capela de Matos, Claudia Diniz, Marcia Trindade Schramm, Juan Clinton Llerena Júnior, Maria Luiza Macedo Silva, Eliana Abdelhay, Teresa de Souza Fernandez
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Molecular Cytogenetics
Subjects:
Myelodysplastic syndrome
Acute myeloid leukemia
Fanconi anemia
Classical cytogenetics
FISH
T(9;11)
Online Access:http://link.springer.com/article/10.1186/s13039-018-0389-x

Internet

http://link.springer.com/article/10.1186/s13039-018-0389-x

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