Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum

Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum

Tuberculous meningitis (TBM) is one of the most severe extrapulmonary manifestations of tuberculosis, with a high morbidity and mortality. Characteristic pathological features of TBM are Rich foci, i.e. brain- and spinal-cord-specific granulomas formed after hematogenous spread of pulmonary tubercul...

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Bibliographic Details
Main Authors: Lisanne M. van Leeuwen, Martijn van der Kuip, Sameh A. Youssef, Alain de Bruin, Wilbert Bitter, A. Marceline van Furth, Astrid M. van der Sar
Format: Article
Language:English
Published: The Company of Biologists 2014-09-01
Series:Disease Models & Mechanisms
Subjects:
Tuberculous meningitis
Tuberculosis
Zebrafish
Mycobacterium marinum
Blood-brain barrier
ESX-1 mutant
Online Access:http://dmm.biologists.org/content/7/9/1111

Internet

http://dmm.biologists.org/content/7/9/1111

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