H2AFZ: A Novel Prognostic Marker in Canine Melanoma and a Predictive Marker for Resistance to CDK4/6 Inhibitor Treatment

by Laura Bongiovanni, Anneloes Andriessen, Serenella Silvestri, Ilaria Porcellato, Chiara Brachelente, Alain de Bruin, Alain de Bruin
Published 2021-08-01

Haploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcoma

by Suma Choorapoikayil, Raoul V. Kuiper, Alain de Bruin, Jeroen den Hertog
Published 2012-03-01

Loss of Pten promotes angiogenesis and enhanced vegfaa expression in zebrafish

by Suma Choorapoikayil, Bart Weijts, Rianne Kers, Alain de Bruin, Jeroen den Hertog
Published 2013-09-01

Correction: Atypical E2fs Control Lymphangiogenesis through Transcriptional Regulation of Ccbe1 and Flt4

by Bart G. M. W. Weijts, Andreas van Impel, Stefan Schulte-Merker, Alain de Bruin
Published 2013-01-01

Atypical E2fs control lymphangiogenesis through transcriptional regulation of Ccbe1 and Flt4.

by Bart G M W Weijts, Andreas van Impel, Stefan Schulte-Merker, Alain de Bruin
Published 2013-01-01

Correction: Atypical E2fs Control Lymphangiogenesis through Transcriptional Regulation of Ccbe1 and Flt4.

by Bart G. M. W. Weijts, Andreas van Impel, Stefan Schulte-Merker, Alain de Bruin
Published 2013-01-01

Rb and p53 Liver Functions Are Essential for Xenobiotic Metabolism and Tumor Suppression.

by Sathidpak Nantasanti, Mathilda J M Toussaint, Sameh A Youssef, Peter C J Tooten, Alain de Bruin
Published 2016-01-01

Evaluating in vivo efficacy – toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells

by Inez Johanna, Trudy Straetemans, Sabine Heijhuurs, Tineke Aarts-Riemens, Håkan Norell, Laura Bongiovanni, Alain de Bruin, Zsolt Sebestyen, Jürgen Kuball
Published 2019-03-01

An ex vivo porcine nasal mucosa explants model to study MRSA colonization.

by Pawel Tulinski, Ad C Fluit, Jos P M van Putten, Alain de Bruin, Sarah Glorieux, Jaap A Wagenaar, Birgitta Duim
Published 2013-01-01

Acute systemic loss of Mad2 leads to intestinal atrophy in adult mice

by Klaske M. Schukken, Yinan Zhu, Petra L. Bakker, Mirjam H. Koster, Liesbeth Harkema, Sameh A. Youssef, Alain de Bruin, Floris Foijer
Published 2021-01-01

Lack of major genome instability in tumors of p53 null rats.

by Roel Hermsen, Pim Toonen, Ewart Kuijk, Sameh A Youssef, Raoul Kuiper, Sebastiaan van Heesch, Alain de Bruin, Edwin Cuppen, Marieke Simonis
Published 2015-01-01

Protection against Influenza A Virus Challenge with M2e-Displaying Filamentous Escherichia coli Phages.

by Lei Deng, Lorena Itatí Ibañez, Veronique Van den Bossche, Kenny Roose, Sameh A Youssef, Alain de Bruin, Walter Fiers, Xavier Saelens
Published 2015-01-01

Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of R-spondin1 in mouse sex reversals

by Nainoa Richardson, Isabelle Gillot, Elodie P Gregoire, Sameh A Youssef, Dirk de Rooij, Alain de Bruin, Marie-Cécile De Cian, Marie-Christine Chaboissier
Published 2020-05-01

Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in HepatocytesSummary

by Ali Saeed, Paulina Bartuzi, Janette Heegsma, Daphne Dekker, Niels Kloosterhuis, Alain de Bruin, Johan W. Jonker, Bart van de Sluis, Klaas Nico Faber
Published 2021-01-01

Correction: Par1b Induces Asymmetric Inheritance of Plasma Membrane Domains via LGN-Dependent Mitotic Spindle Orientation in Proliferating Hepatocytes.

by Christiaan L. Slim, Francisco Lázaro-Diéguez, Marjolein Bijlard, Mathilda J. M. Toussaint, Alain de Bruin, Quansheng Du, Anne Müsch, Sven C. D. van IJzendoorn
Published 2014-01-01

Par1b induces asymmetric inheritance of plasma membrane domains via LGN-dependent mitotic spindle orientation in proliferating hepatocytes.

by Christiaan L Slim, Francisco Lázaro-Diéguez, Marjolein Bijlard, Mathilda J M Toussaint, Alain de Bruin, Quansheng Du, Anne Müsch, Sven C D van Ijzendoorn
Published 2013-12-01

Excessive E2F Transcription in Single Cancer Cells Precludes Transient Cell-Cycle Exit after DNA Damage

by Hendrika A. Segeren, Lotte M. van Rijnberk, Eva Moreno, Frank M. Riemers, Elsbeth A. van Liere, Ruixue Yuan, Richard Wubbolts, Alain de Bruin, Bart Westendorp
Published 2020-12-01

Modeling tuberculous meningitis in zebrafish using Mycobacterium marinum

by Lisanne M. van Leeuwen, Martijn van der Kuip, Sameh A. Youssef, Alain de Bruin, Wilbert Bitter, A. Marceline van Furth, Astrid M. van der Sar
Published 2014-09-01

Atypical E2Fs either Counteract or Cooperate with RB during Tumorigenesis Depending on Tissue Context

by Eva Moreno, Shusil K. Pandit, Mathilda J. M. Toussaint, Laura Bongiovanni, Liesbeth Harkema, Saskia C. van Essen, Elsbeth A. van Liere, Bart Westendorp, Alain de Bruin
Published 2021-04-01

The progeroid phenotype of Ku80 deficiency is dominant over DNA-PKCS deficiency.

by Erwin Reiling, Martijn E T Dollé, Sameh A Youssef, Moonsook Lee, Bhawani Nagarajah, Marianne Roodbergen, Piet de With, Alain de Bruin, Jan H Hoeijmakers, Jan Vijg, Harry van Steeg, Paul Hasty
Published 2014-01-01