A System Out of Breath: How Hypoxia Possibly Contributes to the Pathogenesis of Systemic Sclerosis

Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular alterations and immunological disturbances and fibrosis, the order of which remains to be fully determined. Clinically, patients show clear signs of hypoxia in skin and internal organs. The low oxygen tension is potentially...

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Bibliographic Details
Main Authors: T. W. van Hal, L. van Bon, T. R. D. J. Radstake
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:International Journal of Rheumatology
Online Access:http://dx.doi.org/10.1155/2011/824972