bFGF regulates PI3-kinase-Rac1-JNK pathway and promotes fibroblast migration in wound healing.

bFGF regulates PI3-kinase-Rac1-JNK pathway and promotes fibroblast migration in wound healing.

Fibroblast proliferation and migration play important roles in wound healing. bFGF is known to promote both fibroblast proliferation and migration during the process of wound healing. However, the signal transduction of bFGF-induced fibroblast migration is still unclear, because bFGF can affect both...

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Bibliographic Details
Main Authors: Shigeyuki Kanazawa, Toshihiro Fujiwara, Shinsuke Matsuzaki, Kenta Shingaki, Manabu Taniguchi, Shingo Miyata, Masaya Tohyama, Yasuo Sakai, Kenji Yano, Ko Hosokawa, Tateki Kubo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2923192?pdf=render

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http://europepmc.org/articles/PMC2923192?pdf=render

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