Antidepressive Effects of Kamishoyosan through 5-HT1AReceptor and PKA-CREB-BDNF Signaling in the Hippocampus in Postmenopausal Depression-Model Mice

by Shoko Shimizu, Yugo Ishino, Takashi Takeda, Masaya Tohyama, Shingo Miyata
Published 2019-01-01

Piperine Induces Hepatic Low-Density Lipoprotein Receptor Expression through Proteolytic Activation of Sterol Regulatory Element-Binding Proteins.

by Ayasa Ochiai, Shingo Miyata, Makoto Shimizu, Jun Inoue, Ryuichiro Sato
Published 2015-01-01

Disturbance of Oligodendrocyte Function Plays a Key Role in the Pathogenesis of Schizophrenia and Major Depressive Disorder

by Shingo Miyata, Tsuyoshi Hattori, Shoko Shimizu, Akira Ito, Masaya Tohyama
Published 2015-01-01

The Kampo Medicine Yokukansan Decreases MicroRNA-18 Expression and Recovers Glucocorticoid Receptors Protein Expression in the Hypothalamus of Stressed Mice

by Shoko Shimizu, Takashi Tanaka, Takashi Takeda, Masaya Tohyama, Shingo Miyata
Published 2015-01-01

The endoplasmic reticulum-resident chaperone heat shock protein 47 protects the Golgi apparatus from the effects of O-glycosylation inhibition.

by Shingo Miyata, Tatsunori Mizuno, Yoshihisa Koyama, Taiichi Katayama, Masaya Tohyama
Published 2013-01-01

MARCKSL1 Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors

by Takashi Tanaka, Shoko Shimizu, Masaki Ueno, Yoshitaka Fujihara, Masahito Ikawa, Shingo Miyata
Published 2018-04-01

Yokukansan inhibits neuronal death during ER stress by regulating the unfolded protein response.

by Toru Hiratsuka, Shinsuke Matsuzaki, Shingo Miyata, Mitsuhiro Kinoshita, Kazuaki Kakehi, Shinji Nishida, Taiichi Katayama, Masaya Tohyama
Published 2010-10-01

TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expression.

by Hironori Takamura, Yoshihisa Koyama, Shinsuke Matsuzaki, Kohei Yamada, Tsuyoshi Hattori, Shingo Miyata, Kana Takemoto, Masaya Tohyama, Taiichi Katayama
Published 2012-01-01

L-arginine stimulates fibroblast proliferation through the GPRC6A-ERK1/2 and PI3K/Akt pathway.

by Takashi Fujiwara, Shigeyuki Kanazawa, Ryoko Ichibori, Tomoko Tanigawa, Takuya Magome, Kenta Shingaki, Shingo Miyata, Masaya Tohyama, Ko Hosokawa
Published 2014-01-01

bFGF regulates PI3-kinase-Rac1-JNK pathway and promotes fibroblast migration in wound healing.

by Shigeyuki Kanazawa, Toshihiro Fujiwara, Shinsuke Matsuzaki, Kenta Shingaki, Manabu Taniguchi, Shingo Miyata, Masaya Tohyama, Yasuo Sakai, Kenji Yano, Ko Hosokawa, Tateki Kubo
Published 2010-01-01

Plasma corticosterone activates SGK1 and induces morphological changes in oligodendrocytes in corpus callosum.

by Shingo Miyata, Yoshihisa Koyama, Kana Takemoto, Keiko Yoshikawa, Toshiko Ishikawa, Manabu Taniguchi, Kiyoshi Inoue, Miwa Aoki, Osamu Hori, Taiichi Katayama, Masaya Tohyama
Published 2011-01-01

Dysbindin regulates the transcriptional level of myristoylated alanine-rich protein kinase C substrate via the interaction with NF-YB in mice brain.

by Hiroaki Okuda, Ryusuke Kuwahara, Shinsuke Matsuzaki, Shingo Miyata, Natsuko Kumamoto, Tsuyoshi Hattori, Shoko Shimizu, Kohei Yamada, Keisuke Kawamoto, Ryota Hashimoto, Masatoshi Takeda, Taiichi Katayama, Masaya Tohyama
Published 2010-01-01

Effects of 3 Weeks of Water Immersion and Restraint Stress on Sleep in Mice

by Shinnosuke Yasugaki, Shinnosuke Yasugaki, Chih-Yao Liu, Chih-Yao Liu, Mitsuaki Kashiwagi, Mitsuaki Kashiwagi, Mika Kanuka, Takato Honda, Takato Honda, Shingo Miyata, Masashi Yanagisawa, Masashi Yanagisawa, Masashi Yanagisawa, Yu Hayashi
Published 2019-10-01