Differential effects of integrin-linked kinase inhibitor Cpd22 on severe pulmonary hypertension in male and female rats

Differential effects of integrin-linked kinase inhibitor Cpd22 on severe pulmonary hypertension in male and female rats

Pulmonary arterial hypertension (PAH) is a progressive fatal disease with no cure. Inhibition of integrin-linked kinase (ILK) reverses experimental pulmonary hypertension (PH) in male mice, but its effect on severe experimental PH in either male or female animals is unknown. We examined effects of I...

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Bibliographic Details
Main Authors: Yuanjun Shen, Dmitry A. Goncharov, Theodore Avolio, Arnab Ray, Evelyn Okorie, Horace DeLisser, Ana L. Mora, Rebecca Vanderpool, Tatiana V. Kudryashova, Elena A. Goncharova
Format: Article
Language:English
Published: SAGE Publishing 2020-02-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894019898593

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https://doi.org/10.1177/2045894019898593

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