Tumor suppressors TSC1 and TSC2 differentially modulate actin cytoskeleton and motility of mouse embryonic fibroblasts.

by Elena A Goncharova, Melane L James, Tatiana V Kudryashova, Dmitry A Goncharov, Vera P Krymskaya
Published 2014-01-01

Inhibitory Antibodies against Activin A and TGF-β Reduce Self-Supported, but Not Soluble Factors-Induced Growth of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonar...

by Tatiana V. Kudryashova, Yuanjun Shen, Andressa Pena, Emily Cronin, Evelyn Okorie, Dmitry A. Goncharov, Elena A. Goncharova
Published 2018-09-01

Single-Step qPCR and dPCR Detection of Diverse CRISPR-Cas9 Gene Editing Events In Vivo

by Micol Falabella, Linqing Sun, Justin Barr, Andressa Z. Pena, Erin E. Kershaw, Sebastien Gingras, Elena A. Goncharova, Brett A. Kaufman
Published 2017-10-01

Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right ventricular failure

by Edda Spiekerkoetter, Elena A. Goncharova, Christophe Guignabert, Kurt Stenmark, Grazyna Kwapiszewska, Marlene Rabinovitch, Norbert Voelkel, Harm J. Bogaard, Brian Graham, Soni S. Pullamsetti, Wolfgang M. Kuebler
Published 2019-11-01

Differential effects of integrin-linked kinase inhibitor Cpd22 on severe pulmonary hypertension in male and female rats

by Yuanjun Shen, Dmitry A. Goncharov, Theodore Avolio, Arnab Ray, Evelyn Okorie, Horace DeLisser, Ana L. Mora, Rebecca Vanderpool, Tatiana V. Kudryashova, Elena A. Goncharova
Published 2020-02-01

Wilson Disease: Intersecting DNA Methylation and Histone Acetylation Regulation of Gene Expression in a Mouse Model of Hepatic Copper AccumulationSummary

by Gaurav V. Sarode, Kari Neier, Noreene M. Shibata, Yuanjun Shen, Dmitry A. Goncharov, Elena A. Goncharova, Tagreed A. Mazi, Nikhil Joshi, Matthew L. Settles, Janine M. LaSalle, Valentina Medici
Published 2021-01-01

HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension

by Olivier Boucherat, Sophie Chabot, Roxane Paulin, Isabelle Trinh, Alice Bourgeois, François Potus, Marie-Claude Lampron, Caroline Lambert, Sandra Breuils-Bonnet, Valérie Nadeau, Renée Paradis, Elena A. Goncharova, Steeve Provencher, Sébastien Bonnet
Published 2017-07-01

Folliculin, the product of the Birt-Hogg-Dube tumor suppressor gene, interacts with the adherens junction protein p0071 to regulate cell-cell adhesion.

by Doug A Medvetz, Damir Khabibullin, Venkatesh Hariharan, Pat P Ongusaha, Elena A Goncharova, Tanja Schlechter, Thomas N Darling, Ilse Hofmann, Vera P Krymskaya, James K Liao, Hayden Huang, Elizabeth P Henske
Published 2012-01-01

Folliculin Controls Lung Alveolar Enlargement and Epithelial Cell Survival through E-Cadherin, LKB1, and AMPK

by Elena A. Goncharova, Dmitry A. Goncharov, Melane L. James, Elena N. Atochina-Vasserman, Victoria Stepanova, Seung-Beom Hong, Hua Li, Linda Gonzales, Masaya Baba, W. Marston Linehan, Andrew J. Gow, Susan Margulies, Susan Guttentag, Laura S. Schmidt, Vera P. Krymskaya
Published 2014-04-01

Functional NMDA receptors are expressed by human pulmonary artery smooth muscle cells

by Yi Na Dong, Fu-Chun Hsu, Cynthia J. Koziol-White, Victoria Stepanova, Joseph Jude, Andrei Gritsiuta, Ryan Rue, Rosalind Mott, Douglas A. Coulter, Reynold A. Panettieri, Vera P. Krymskaya, Hajime Takano, Elena A. Goncharova, Dmitry A. Goncharov, Douglas B. Cines, David R. Lynch
Published 2021-04-01

Distinct plasma gradients of microRNA-204 in the pulmonary circulation of patients suffering from WHO Groups I and II pulmonary hypertension

by Leonard E. Estephan, Michael V. Genuardi, Chad M. Kosanovich, Michael G. Risbano, Yingze Zhang, Nancy Petro, Annie Watson, Yassmin Al Aaraj, John C. Sembrat, Mauricio Rojas, Dmitry A. Goncharov, Marc A. Simon, Elena A. Goncharova, Anjali Vaidya, Akaya Smith, Jeremy Mazurek, Yuchi Han, Stephen Y. Chan
Published 2019-03-01