The Future of Regulatory T Cell Therapy: Promises and Challenges of Implementing CAR Technology

Cell therapy with polyclonal regulatory T cells (Tregs) has been translated into the clinic and is currently being tested in transplant recipients and patients suffering from autoimmune diseases. Moreover, building on animal models, it has been widely reported that antigen-specific Tregs are functio...

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Bibliographic Details
Main Authors: Yasmin R. Mohseni, Sim L. Tung, Caroline Dudreuilh, Robert I. Lechler, Gilbert O. Fruhwirth, Giovanna Lombardi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01608/full