Illumina error correction near highly repetitive DNA regions improves de novo genome assembly

Illumina error correction near highly repetitive DNA regions improves de novo genome assembly

Abstract Background Several standalone error correction tools have been proposed to correct sequencing errors in Illumina data in order to facilitate de novo genome assembly. However, in a recent survey, we showed that state-of-the-art assemblers often did not benefit from this pre-correction step....

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Bibliographic Details
Main Authors: Mahdi Heydari, Giles Miclotte, Yves Van de Peer, Jan Fostier
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Bioinformatics
Subjects:
Illumina sequencing data
De novo genome assembly
Error correction
De Bruijn Graph
Community detection
Online Access:http://link.springer.com/article/10.1186/s12859-019-2906-2

Internet

http://link.springer.com/article/10.1186/s12859-019-2906-2

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