Increased fucoxanthin in Chaetoceros calcitrans extract exacerbates apoptosis in liver cancer cells via multiple targeted cellular pathways

In this study, anti-proliferative effects of C. calcitrans extract and its fucoxanthin rich fraction (FxRF) were assessed on human liver HepG2 cancer cell line. Efficacy from each extract was determined by cytotoxicity assay, morphological observation, and cell cycle analysis. Mechanisms of action o...

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Bibliographic Details
Main Authors: Su Chern Foo, Fatimah Md. Yusoff, Mustapha Umar Imam, Jhi Biau Foo, Norsharina Ismail, Nur Hanisah Azmi, Yin Sim Tor, Nicholas M.H. Khong, Maznah Ismail
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Biotechnology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X18302443