Treatment of irradiated mice with high-dose ascorbic acid reduced lethality.

Ascorbic acid is an effective antioxidant and free radical scavenger. Therefore, it is expected that ascorbic acid should act as a radioprotectant. We investigated the effects of post-radiation treatment with ascorbic acid on mouse survival. Mice received whole body irradiation (WBI) followed by int...

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Bibliographic Details
Main Authors: Tomohito Sato, Manabu Kinoshita, Tetsuo Yamamoto, Masataka Ito, Takafumi Nishida, Masaru Takeuchi, Daizoh Saitoh, Shuhji Seki, Yasuo Mukai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4317183?pdf=render