Toxoplasma DJ-1 Regulates Organelle Secretion by a Direct Interaction with Calcium-Dependent Protein Kinase 1

Toxoplasma DJ-1 Regulates Organelle Secretion by a Direct Interaction with Calcium-Dependent Protein Kinase 1

Human DJ-1 is a highly conserved and yet functionally enigmatic protein associated with a heritable form of Parkinson’s disease. It has been suggested to be a redox-dependent regulatory scaffold, binding to proteins to modulate their function. Here we present the X-ray crystal structure of the Toxop...

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Bibliographic Details
Main Authors: Matthew A. Child, Megan Garland, Ian Foe, Peter Madzelan, Moritz Treeck, Wouter A. van der Linden, Kristina Oresic Bender, Eranthie Weerapana, Mark A. Wilson, John C. Boothroyd, Michael L. Reese, Matthew Bogyo, Jon P. Boyle
Format: Article
Language:English
Published: American Society for Microbiology 2017-02-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/1/e02189-16

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http://mbio.asm.org/cgi/content/full/8/1/e02189-16

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