SLy2‐deficiency promotes B‐1 cell immunity and triggers enhanced production of IgM and IgG2 antibodies against pneumococcal vaccine

SLy2‐deficiency promotes B‐1 cell immunity and triggers enhanced production of IgM and IgG2 antibodies against pneumococcal vaccine

Abstract Background Despite the benefits of existing vaccines, Streptococcus pneumoniae is still responsible for the greatest proportion of respiratory tract infections around the globe, thereby substantially contributing to morbidity and mortality in humans. B‐1 cells are key players of bacterial c...

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Bibliographic Details
Main Authors: Jennifer Jaufmann, Leyla Tümen, Fee Schmitt, Daniel Schäll, Max vonHolleben, Sandra Beer‐Hammer
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:Immunity, Inflammation and Disease
Subjects:
antibody responses
B‐1 cells
natural IgM
pneumococcal vaccination
pneumonia
Src homology domain 3 lymphocyte protein 2
Online Access:https://doi.org/10.1002/iid3.365

Internet

https://doi.org/10.1002/iid3.365

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