Function, Regulation and Biological Roles of PI3Kγ Variants

by Bernd Nürnberg, Sandra Beer-Hammer
Published 2019-08-01

SLy2‐overexpression impairs B‐cell development in the bone marrow and the IgG response towards pneumococcal conjugate‐vaccine

by Jennifer Jaufmann, Leyla Tümen, Sandra Beer‐Hammer
Published 2021-06-01

Analyses of Gnai3-iresGFP reporter mice reveal unknown Gαi3 expression sites

by Veronika Leiss, Ellen Reisinger, Annika Speidel, Sandra Beer-Hammer, Bernd Nürnberg
Published 2021-07-01

The gut microbiota metabolite urolithin A inhibits NF-κB activation in LPS stimulated BMDMs

by Khalid N. M. Abdelazeem, M. Zaher Kalo, Sandra Beer-Hammer, Florian Lang
Published 2021-03-01

SLy2‐deficiency promotes B‐1 cell immunity and triggers enhanced production of IgM and IgG2 antibodies against pneumococcal vaccine

by Jennifer Jaufmann, Leyla Tümen, Fee Schmitt, Daniel Schäll, Max vonHolleben, Sandra Beer‐Hammer
Published 2020-12-01

Enhanced IgG1‐mediated antibody response towards thymus‐dependent immunization in CXCR1‐deficient mice

by Jennifer Jaufmann, Melanie Carevic, Leyla Tümen, Derya Eliacik, Fee Schmitt, Dominik Hartl, Sandra Beer‐Hammer
Published 2021-03-01

RXFP1 Receptor Activation by Relaxin-2 Induces Vascular Relaxation in Mice via a Gαi2-Protein/PI3Kß/γ/Nitric Oxide-Coupled Pathway

by Xiaoming Lian, Sandra Beer-Hammer, Gabriele M. König, Evi Kostenis, Bernd Nürnberg, Maik Gollasch, Maik Gollasch
Published 2018-09-01

Neuroprotective, Neurogenic, and Amyloid Beta Reducing Effect of a Novel Alpha 2-Adrenoblocker, Mesedin, on Astroglia and Neuronal Progenitors upon Hypoxia and Glutamate Exposure

by Magda M. Melkonyan, Lilit Hunanyan, Ali Lourhmati, Nikolas Layer, Sandra Beer-Hammer, Konstantin Yenkoyan, Matthias Schwab, Lusine Danielyan
Published 2017-12-01

p110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway Inflammation.

by Benedikt Mothes, Kirsten Bucher, Susanne Ammon-Treiber, Matthias Schwab, Roland P Piekorz, Emilio Hirsch, Bernd Nürnberg, Sandra Beer-Hammer
Published 2016-01-01

Correction: p110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway Inflammation.

by Benedikt Mothes, Kirsten Bucher, Susanne Ammon-Treiber, Matthias Schwab, Roland P Piekorz, Emilio Hirsch, Bernd Nürnberg, Sandra Beer-Hammer
Published 2016-01-01

Deficiency of PI3-Kinase catalytic isoforms p110γ and p110δ in mice enhances the IL-17/G-CSF axis and induces neutrophilia

by Kirsten Bucher, Fee Schmitt, Benedikt Mothes, Carolin Blumendeller, Daniel Schäll, Roland Piekorz, Emilio Hirsch, Bernd Nürnberg, Sandra Beer-Hammer
Published 2017-07-01

mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo.

by Franziska Zeyer, Benedikt Mothes, Clara Will, Melanie Carevic, Jennifer Rottenberger, Bernd Nürnberg, Dominik Hartl, Rupert Handgretinger, Sandra Beer-Hammer, Michael S D Kormann
Published 2016-01-01

Correction: mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo.

by Franziska Zeyer, Benedikt Mothes, Clara Will, Melanie Carevic, Jennifer Rottenberger, Bernd Nürnberg, Dominik Hartl, Rupert Handgretinger, Sandra Beer-Hammer, Michael S D Kormann
Published 2018-01-01

Dataset on the activation of Müller cells through macrophages upon hypoxia in the retina

by Christina Nürnberg, Norbert Kociok, Claudia Brockmann, Timo Lischke, Sergio Crespo-Garcia, Nadine Reichhart, Susanne Wolf, Ria Baumgrass, Sabine A. Eming, Sandra Beer-Hammer, Antonia M. Joussen
Published 2018-02-01

Gαi2- and Gαi3-deficient mice display opposite severity of myocardial ischemia reperfusion injury.

by David Köhler, Vasudharani Devanathan, Claudia Bernardo de Oliveira Franz, Therese Eldh, Ana Novakovic, Judith M Roth, Tiago Granja, Lutz Birnbaumer, Peter Rosenberger, Sandra Beer-Hammer, Bernd Nürnberg
Published 2014-01-01

Myeloid-Derived Suppressor Cells Dampen Airway Inflammation Through Prostaglandin E2 Receptor 4

by Chiel van Geffen, Chiel van Geffen, Chiel van Geffen, Astrid Deißler, Sandra Beer-Hammer, Bernd Nürnberg, Rupert Handgretinger, Harald Renz, Harald Renz, Dominik Hartl, Dominik Hartl, Saeed Kolahian, Saeed Kolahian, Saeed Kolahian
Published 2021-07-01

Intranasal Delivery of Bone Marrow-Derived Mesenchymal Stem Cells, Macrophages, and Microglia to the Brain in Mouse Models of Alzheimer's and Parkinson's Disease

by Lusine Danielyan, Sandra Beer-Hammer, Alexandra Stolzing, Richard Schäfer, Georg Siegel, Claire Fabian, Philipp Kahle, Tilo Biedermann, Ali Lourhmati, Marine Buadze, Ana Novakovic, Barbara Proksch, Christoph H. Gleiter, William H. Frey, Matthias Schwab
Published 2014-01-01

Depletion of dendritic cells enhances innate anti-bacterial host defense through modulation of phagocyte homeostasis.

by Stella E Autenrieth, Philipp Warnke, Guido H Wabnitz, Cecilia Lucero Estrada, Karina A Pasquevich, Doreen Drechsler, Manina Günter, Kristin Hochweller, Ana Novakovic, Sandra Beer-Hammer, Yvonne Samstag, Günter J Hämmerling, Natalio Garbi, Ingo B Autenrieth
Published 2012-02-01

Defective Gpsm2/Gαi3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome

by Stephanie A. Mauriac, Yeri E. Hien, Jonathan E. Bird, Steve Dos-Santos Carvalho, Ronan Peyroutou, Sze Chim Lee, Maite M. Moreau, Jean-Michel Blanc, Aysegul Gezer, Chantal Medina, Olivier Thoumine, Sandra Beer-Hammer, Thomas B. Friedman, Lukas Rüttiger, Andrew Forge, Bernd Nürnberg, Nathalie Sans, Mireille Montcouquiol
Published 2017-04-01

Correction: Author Correction: Defective Gpsm2/Gαi3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome

by Stephanie A. Mauriac, Yeri E. Hien, Jonathan E. Bird, Steve Dos-Santos Carvalho, Ronan Peyroutou, Sze Chim Lee, Maite M. Moreau, Jean-Michel Blanc, Aysegul Gezer, Chantal Medina, Olivier Thoumine, Sandra Beer-Hammer, Thomas B. Friedman, Lukas Rüttiger, Andrew Forge, Bernd Nürnberg, Nathalie Sans, Mireille Montcouquiol
Published 2018-05-01