Abstract P-19: 15-Microsecond Molecular Dynamics Simulations of Nucleosome Show Structural Heterogeneity and Plasticity

Abstract P-19: 15-Microsecond Molecular Dynamics Simulations of Nucleosome Show Structural Heterogeneity and Plasticity

Background: Nucleosomes are basic units of chromatin organization, resembling spools with ~150 base pairs of DNA wrapped around the octamer of histone proteins. They play a crucial role in chromatin compactization and gene expression. Currently, there are more than 340 structures of nucleosomes and...

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Bibliographic Details
Main Authors: Grigoriy A. Armeev, Anastasiia S. Kniazeva, Galina A. Komarova, Mikhail P. Kirpichnikov, Alexey K. Shaytan
Format: Article
Language:English
Published: International Medical Research and Development Corporation 2021-06-01
Series:International Journal of Biomedicine
Subjects:
nucleosome
chromatin
molecular dynamics
Online Access:http://ijbm.org/articles/v11s1/ijbm_2021_11_s1_p19.pdf

Internet

http://ijbm.org/articles/v11s1/ijbm_2021_11_s1_p19.pdf

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