An expanded variant list and assembly annotation identifies multiple novel coding and noncoding genes for prostate cancer risk using a normal prostate tissue eQTL data set.

An expanded variant list and assembly annotation identifies multiple novel coding and noncoding genes for prostate cancer risk using a normal prostate tissue eQTL data set.

Prostate cancer (PrCa) is highly heritable; 284 variants have been identified to date that are associated with increased prostate cancer risk, yet few genes contributing to its development are known. Expression quantitative trait loci (eQTL) studies link variants with affected genes, helping to dete...

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Bibliographic Details
Main Authors: Melissa S DeRycke, Melissa C Larson, Asha A Nair, Shannon K McDonnell, Amy J French, Lori S Tillmans, Shaun M Riska, Saurabh Baheti, Zachary C Fogarty, Nicholas B Larson, Daniel R O'Brien, John C Cheville, Liang Wang, Daniel J Schaid, Stephen N Thibodeau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214588

Internet

https://doi.org/10.1371/journal.pone.0214588

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