Time-course transcriptome analysis of human cellular reprogramming from multiple cell types reveals the drastic change occurs between the mid phase and the late phase

Time-course transcriptome analysis of human cellular reprogramming from multiple cell types reveals the drastic change occurs between the mid phase and the late phase

Abstract Background Human induced pluripotent stem cells (hiPSCs) have been attempted for clinical application with diverse iPSCs sources derived from various cell types. This proposes that there would be a shared reprogramming route regardless of different starting cell types. However, the insights...

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Bibliographic Details
Main Authors: Akihiro Kuno, Ken Nishimura, Satoru Takahashi
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Genomics
Subjects:
Induced pluripotent stem cell
Cellular reprogramming
Time-course gene expression
Transcriptional factor
Transcriptional factor regulatory network
Online Access:http://link.springer.com/article/10.1186/s12864-017-4389-8

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http://link.springer.com/article/10.1186/s12864-017-4389-8

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