Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection.

Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection.

HIV/SIV infections break down the integrity of the gastrointestinal mucosa and lead to chronic immune activation and associated disease progression. Innate lymphoid cells (ILCs), distinguishable by high expression of NKp44 and RORγt, play key roles in mucosal defense and homeostasis, but are deplete...

Full description

Bibliographic Details
Main Authors: Haiying Li, Laura E Richert-Spuhler, Tristan I Evans, Jacqueline Gillis, Michelle Connole, Jacob D Estes, Brandon F Keele, Nichole R Klatt, R Keith Reeves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4263758?pdf=render

Internet

http://europepmc.org/articles/PMC4263758?pdf=render

Similar Items