The Biological Potential Hidden in Inclusion Bodies

The Biological Potential Hidden in Inclusion Bodies

Inclusion bodies (IBs) are protein nanoclusters obtained during recombinant protein production processes, and several studies have demonstrated their potential as biomaterials for therapeutic protein delivery. Nevertheless, IBs have been, so far, exclusively sifted by their biological activity in vi...

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Bibliographic Details
Main Authors: Laia Gifre-Renom, Joaquin Seras-Franzoso, Diana Rafael, Fernanda Andrade, Olivia Cano-Garrido, Francesc Martinez-Trucharte, Estefania Ugarte-Berzal, Erik Martens, Lise Boon, Antonio Villaverde, Ghislain Opdenakker, Simó Schwartz, Anna Arís, Elena Garcia-Fruitós
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Pharmaceutics
Subjects:
inclusion body
polymeric micelle
stability
matrix metalloproteinase-9
in vitro
in vivo
Online Access:https://www.mdpi.com/1999-4923/12/2/157

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https://www.mdpi.com/1999-4923/12/2/157

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