Dynamic modelling under uncertainty: the case of Trypanosoma brucei energy metabolism.

Kinetic models of metabolism require detailed knowledge of kinetic parameters. However, due to measurement errors or lack of data this knowledge is often uncertain. The model of glycolysis in the parasitic protozoan Trypanosoma brucei is a particularly well analysed example of a quantitative metabol...

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Bibliographic Details
Main Authors: Fiona Achcar, Eduard J Kerkhoven, SilicoTryp Consortium, Barbara M Bakker, Michael P Barrett, Rainer Breitling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22379410/?tool=EBI