The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitors.

The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitors.

Primary osteoporosis is an age-related disease characterized by an imbalance in bone homeostasis. While the resorptive aspect of the disease has been studied intensely, less is known about the anabolic part of the syndrome or presumptive deficiencies in bone regeneration. Multipotent mesenchymal ste...

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Bibliographic Details
Main Authors: Peggy Benisch, Tatjana Schilling, Ludger Klein-Hitpass, Sönke P Frey, Lothar Seefried, Nadja Raaijmakers, Melanie Krug, Martina Regensburger, Sabine Zeck, Thorsten Schinke, Michael Amling, Regina Ebert, Franz Jakob
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3454401?pdf=render

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http://europepmc.org/articles/PMC3454401?pdf=render

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