Chemokines in Physiological and Pathological Bone Remodeling

by Laura J. Brylka, Thorsten Schinke
Published 2019-09-01

Deficiency of sphingosine-1-phosphate receptor 3 does not affect the skeletal phenotype of mice lacking sphingosine-1-phosphate lyase.

by Timo Heckt, Laura J Brylka, Mona Neven, Michael Amling, Thorsten Schinke
Published 2019-01-01

Divergent resorbability and effects on osteoclast formation of commonly used bone substitutes in a human in vitro-assay.

by Johannes Keller, Silja Brink, Björn Busse, Arndt F Schilling, Thorsten Schinke, Michael Amling, Tobias Lange
Published 2012-01-01

Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing.

by Stephanie Bergdolt, Anna Kovtun, Yvonne Hägele, Astrid Liedert, Thorsten Schinke, Michael Amling, Markus Huber-Lang, Anita Ignatius
Published 2017-01-01

Midkine-deficiency delays chondrogenesis during the early phase of fracture healing in mice.

by Melanie Haffner-Luntzer, Aline Heilmann, Anna Elise Rapp, Simon Beie, Thorsten Schinke, Michael Amling, Anita Ignatius, Astrid Liedert
Published 2014-01-01

The clock genes Period 2 and Cryptochrome 2 differentially balance bone formation.

by Erik Maronde, Arndt F Schilling, Sebastian Seitz, Thorsten Schinke, Isabelle Schmutz, Gijsbertus van der Horst, Michael Amling, Urs Albrecht
Published 2010-01-01

Deficiency of Thrombospondin-4 in Mice Does Not Affect Skeletal Growth or Bone Mass Acquisition, but Causes a Transient Reduction of Articular Cartilage Thickness.

by Anke Jeschke, Martin Bonitz, Maciej Simon, Stephanie Peters, Wolfgang Baum, Georg Schett, Wolfgang Ruether, Andreas Niemeier, Thorsten Schinke, Michael Amling
Published 2015-01-01

Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis

by Nico Hinz, Anke Baranowsky, Michael Horn, Malte Kriegs, Freya Sibbertsen, Daniel J. Smit, Philippe Clezardin, Tobias Lange, Thorsten Schinke, Manfred Jücker
Published 2021-02-01

Accelerated tooth movement in Rsk2-deficient mice with impaired cementum formation

by Cita Nottmeier, Maximilian G. Decker, Julia Luther, Simon von Kroge, Bärbel Kahl-Nieke, Michael Amling, Thorsten Schinke, Julian Petersen, Till Koehne
Published 2020-12-01

The Wnt serpentine receptor Frizzled-9 regulates new bone formation in fracture healing.

by Aline Heilmann, Thorsten Schinke, Ronny Bindl, Tim Wehner, Anna Rapp, Melanie Haffner-Luntzer, Claudia Nemitz, Astrid Liedert, Michael Amling, Anita Ignatius
Published 2013-01-01

Skeletal deterioration in COL2A1-related spondyloepiphyseal dysplasia occurs prior to the development of osteoarthritis

by Tim Rolvien, Timur A. Yorgan, Uwe Kornak, Irm Hermans-Borgmeyer, Stefan Mundlos, Tobias Schmidt, Andreas Niemeier, Thorsten Schinke, Michael Amling, Ralf Oheim
Published 2020-10-01

Inhibition of Midkine Augments Osteoporotic Fracture Healing.

by Melanie Haffner-Luntzer, Julia Kemmler, Verena Heidler, Katja Prystaz, Thorsten Schinke, Michael Amling, Anna Kovtun, Anna E Rapp, Anita Ignatius, Astrid Liedert
Published 2016-01-01

Osteoblast-specific Krm2 overexpression and Lrp5 deficiency have different effects on fracture healing in mice.

by Astrid Liedert, Viktoria Röntgen, Thorsten Schinke, Peggy Benisch, Regina Ebert, Franz Jakob, Ludger Klein-Hitpass, Jochen K Lennerz, Michael Amling, Anita Ignatius
Published 2014-01-01

TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality

by Frederike Sass, Christian Schlein, Michelle Y. Jaeckstein, Paul Pertzborn, Michaela Schweizer, Thorsten Schinke, Andrea Ballabio, Ludger Scheja, Joerg Heeren, Alexander W. Fischer
Published 2021-05-01

The impact of low-magnitude high-frequency vibration on fracture healing is profoundly influenced by the oestrogen status in mice

by Esther Wehrle, Astrid Liedert, Aline Heilmann, Tim Wehner, Ronny Bindl, Lena Fischer, Melanie Haffner-Luntzer, Franz Jakob, Thorsten Schinke, Michael Amling, Anita Ignatius
Published 2015-01-01

The Protein Tyrosine Phosphatase Rptpζ Suppresses Osteosarcoma Development in Trp53-Heterozygous Mice.

by Christina Baldauf, Anke Jeschke, Vincent Kanbach, Philip Catala-Lehnen, Daniel Baumhoer, Helwe Gerull, Sophia Buhs, Michael Amling, Peter Nollau, Sheila Harroch, Thorsten Schinke
Published 2015-01-01

Increased osteoclastogenesis in mice lacking the carcinoembryonic antigen-related cell adhesion molecule 1.

by Timo Heckt, Thomas Bickert, Anke Jeschke, Sebastian Seitz, Jochen Schulze, Wulf D Ito, Wolfgang Zimmermann, Michael Amling, Thorsten Schinke, Andrea Kristina Horst, Johannes Keller
Published 2014-01-01

Loss of murine Gfi1 causes neutropenia and induces osteoporosis depending on the pathogen load and systemic inflammation.

by Sven Geissler, Martin Textor, Sabine Stumpp, Sebastian Seitz, Anja Lekaj, Sabrina Brunk, Sabine Klaassen, Thorsten Schinke, Christoph Klein, Stefan Mundlos, Uwe Kornak, Jirko Kühnisch
Published 2018-01-01

Mice carrying a ubiquitous R235W mutation of Wnt1 display a bone-specific phenotype

by Timur Alexander Yorgan, Tim Rolvien, Julian Stürznickel, Nele Vollersen, Fabiola Lange, Anke Baranowsky, Irm Hermans-Borgmeyer, Jean-Pierre David, Ralf Oheim, Michael Amling, Thorsten Schinke
Published 2020-10-01

Lethal osteogenesis imperfecta type XX caused by compound heterozygous frameshift mutations in MESD

by Julian Stürznickel, Katharina Jaehn-Rickert, Jozef Zustin, Maximilian M. Delsmann, Helga Rehder, Anna Floriane Hennig, Katharina Schoner, Alfons Kreczy, Thorsten Schinke, Michael Amling, Uwe Kornak
Published 2021-04-01